20, March 2025

Brain-Eating Amoeba: Symptoms, Diagnosis, Treatment, and Prevention

Although the number of brain-eating amoeba (Naegleria fowleri) infections is increasing, the information about this lethal organism is very uncommon among common people. Found in warm waters, it enters the body by the nose and quickly damages brain tissue, leading to primary amebic meningoencephalitis (PAM), a fatal disorder that has a less than 5% chance of survival. Unfortunately, PAM has claimed the lives of almost 97% of its victims. Due to early symptoms that resemble common illnesses, detection is delayed, compromising the treatment effectiveness. In order to lower the chances of this disease and save more & more lives, it is essential that people take immediate awareness and preventative actions, such as avoiding using polluted water and wearing appropriate nose protection, since rising global temperatures create more conducive conditions for its spread.

In the following article we are going to share some facts on: What is this dreadful micro-organism? In what way does it enter the brain? How can I suspect this infection at early stages? How can I prevent it?

What is Brain-Eating Amoeba?

The amoeba Naegleria fowleri inhabits warm, shallow freshwater bodies including lakes, rivers, and hot springs all throughout the world. It inhabits dirty garbage as well. It is regarded as a free-living micro-organism as it can survive without a host. When this amoeba infects a person, the result is primary amoebic meningoencephalitis (PAM). PAM is an extremely dangerous and nearly invariably lethal infection of the central nervous system.

What are the Causes of Brain-Eating Amoeba?

This kind of amoeba infection most frequently occurs when contaminated water enters your nose. The amoeba then travels to your brain. This often occurs while you're swimming, diving, or water skiing in contaminated water. Rarely, warm tap water or inadequately chlorinated pool water may be the source of the infection. However, swallowing contaminated water cannot infect you. Very warm water is ideal for this organism's survival. Water as hot as 115 F is safe for it to live in. Warm climates are home to these amoebas. It cannot survive in salt water or chlorine-treated water. N. fowleri can flourish in:

Warm lakes
Ponds
Rock pits
Mud puddles
Warm, slow-flowing rivers
Contaminated swimming pools and spas
Contaminated well water or untreated municipal water
Hot springs and other geothermal water sources
Thermally polluted water, such as runoff from power plants
Soil, including indoor dust
Aquariums
Water parks
Splash pads for children

What are the Symptoms of Brain-Eating Amoeba?

The symptoms of PAM are not exclusive to this condition. PAM initially could resemble viral meningitis. Some of the symptoms are:

Headache
Fever
Stiff Neck
Loss Of Appetite
Vomiting
Altered Mental State
Seizures
Coma
Hallucinations
Drooping Eyelid
Blurred vision
Loss of the sense of taste

How is Brain-Eating Amoeba Diagnosed?

Your doctor may suggest a brain biopsy, in which a tissue sample is taken and examined under a microscope to check for the presence of the brain-eating amoeba (Naegleria fowleri). If they believe you may have been infected by the organism, they may also suggest a spinal tap, also known as a lumbar puncture, to see if the organism is in your cerebrospinal fluid (CSF).

What is the Treatment of Brain-Eating Amoeba?

The antifungal amphotericin B is the preferred therapy for primary amoebic meningoencephalitis (PAM), also known as infection with the brain-eating amoeba (Naegleria fowleri). Amphotericin B, rifampin, fluconazole, and a medication known as miltefosine were among the medications used to treat some survivors in North America. A medication called miltefosine is authorized to treat leishmaniasis, a parasitic illness that is transmitted by sandflies.

Early identification and treatment with the prescribed medications, together with lowering body temperature below normal to treat brain swelling, yielded the most favourable outcomes (in two children who recovered fully).

Prevention Tips for Brain-Eating Amoeba

Even though the disease is quite rare, prevention might be crucial because of the dismal prognosis. These are important points to keep in mind:

Wearing noseplugs is advised for swimming, wading, or participating in water sports in warm freshwater environments, particularly calm waters. If there is a known or probable presence of Naegleria fowleri in the water, avoid going in at all.
When using a neti pot or any other nasal cleansing device, avoid using tap water. Use only sterilized or distilled water. Be careful to boil the tap water for one minute and then allow it to cool if you want to use it. Boil the water for three minutes and then allow it to cool if you reside 6,500 feet above sea level.
Filters can be used to cleanse water of microorganisms. Use filters with "absolute pore size of 1 micron or smaller," "NSF 53," or "NSF 58."
To clear your sinuses and nose, you may also disinfect your water using chlorine bleach pills or liquid. The amount of bleach needed to disinfect drinking water is different than that needed to disinfect nose water.
Inform the doctor where you have been if you get fever or headache symptoms after entering warm waters.

Conclusion

It is indeed frightening to learn about a disease brought on by a brain-eating amoeba and to realize how serious it may be. Seek medical attention right away if you believe you may have come into contact with the amoeba. However, it's crucial to keep in mind how uncommon this illness is. By rinsing your nasal passages with only distilled or sterilized water and avoiding water you fear may be contaminated, particularly during hot weather, you may help prevent it.

Learn about the symptoms, diagnosis, treatment options, and prevention tips for brain-eating amoeba (Naegleria fowleri). Stay informed with IBS Hospital. Book your consultation now!

FAQs

Q1: How does someone get infected with Naegleria fowleri?
A: Infection occurs when contaminated water enters the nose, usually while swimming or diving in warm freshwater. The amoeba then travels to the brain, where it causes severe inflammation and destruction of brain tissue.

Q2: Can you get infected by drinking contaminated water?
A: No, Naegleria fowleri infection occurs only when water enters the nasal passages. Swallowing contaminated water does not cause infection.

Q3: What should I do if I suspect an infection?
A: Seek immediate medical attention if you or someone you know develops severe headaches, fever, nausea, or neurological symptoms after recent freshwater exposure. Early diagnosis and aggressive treatment may improve survival chances.

Q4: Is treatment for primary amebic meningoencephalitis (PAM) available in India?
A: Yes, treatment for Naegleria fowleri infection is available in India. Hospitals with advanced critical care and infectious disease departments may offer treatments like Amphotericin B, Miltefosine, and therapeutic hypothermia

By -Dr Aaksha Shukla | March 20, 2025 | 9 Min Read